A 7-year-old male French Bulldog was referred to discuss radiation therapy for a right piriform lobe tumour suspected to be a glioma based on imaging characteristics.
The patient reportedly had his first seizure in December 2016 after a rigorous walk. He was started on 45mg phenobarbital twice daily at that time and di reasonably well until a recent onset of further seizure activity in June 2017. This prompted further evaluation at a referral hospital where an MRI diagnosed an approximately 2 x 1.5cm diameter intra-axial mass in the right piriform lobe.
Given the lesion location surgery was not a viable option and the patient was referred to the oncology team for evaluation for radiation therapy. CT simulation for stereotactic radiation therapy was done on 26/6/2017. These images were fused with the MRI for radiation planning.
The patient tolerated the treatment very well with no acute adverse effects. A follow up MRI done 3 months later showed significant mass reduction. In July 2018 (13 months post SRT) the patient had several additional seizures. A repeat MRI at this time showed the mass remained markedly reduced in size. His anti-epileptic medications were adjusted, and the seizures were controlled again. At 14 months post SRT the patient was clinically stable with a normal neurological examination. The patient passed away 21 months after diagnosis.